This has been happening quite often, Premiere will lock up with the color wheel when I double-click RED media into the source window. I can't diagnose the cause, but I think there may be a conflict between the autosave and opening a clip. When I force quit the app, I get the notification dialog box saying Premiere is attempting to save, as well as the progress bar box from the autosave trying to save, but it doesn't. Perhaps it's trying to do two things at once?
I'm using 8K clips and linking to the Monstro's auto-generated 2K proxies in the same folder directory. My media is spanned across eight drives using two USB-C 4-bay enclosures. I don't think speed is an issue, but I'm on the latest version of Premiere. It wasn't doing this before the 13.0.2.